The Science Behind myThalamus
Every feature on this platform is informed by published, peer-reviewed research. Here are the key studies that shape our approach to cognitive health.
Three Pillars of Our Approach
Neural Stimulation
40 Hz audio entrainment to promote gamma oscillations associated with memory and attention.
Cognitive Training
Speed of processing, memory, and reaction time exercises based on the ACTIVE Trial protocol.
Daily Habit Tracking
Streak-based accountability system that builds the consistency needed for long-term cognitive benefits.
Key Research Studies
ACTIVE Trial — 20-Year Follow-Up
Alzheimer's & Dementia: TRC&I, 2026
Speed of processing training was associated with 25% lower dementia incidence over 20 years — the first non-drug intervention linked to this outcome.
ACTIVE Trial — Driving Safety
Journal of the American Geriatrics Society
Speed of processing training was associated with 50% fewer at-fault crashes and 40% longer driving continuation.
40 Hz Gamma Entrainment (MIT)
Nature, 2016 & Cell, 2019
40 Hz sensory stimulation was associated with reduced amyloid plaques and tau tangles in Alzheimer's mouse models, with human trials now underway at MIT.
FINGER Trial
The Lancet, 2015
Multi-domain lifestyle intervention (exercise, diet, cognitive training, vascular monitoring) improved overall cognitive function by 25% compared to control.
Lion's Mane Mushroom — Cognitive Function
Phytotherapy Research, 2009
Older adults taking Lion's Mane for 16 weeks showed significant improvement on cognitive function scales compared to placebo.
NeuroRacer — Multitasking Training
Nature, 2013
Custom video game training improved multitasking ability in older adults to levels exceeding untrained 20-year-olds, with benefits lasting 6 months.
Explore the Interactive Brain Map
See exactly which brain regions each myThalamus training tool targets — and why it matters for driving safety and cognitive health.
Open Brain MapImportant Note
myThalamus is a wellness and cognitive training platform, not a medical device. The studies cited above inform our approach but do not constitute clinical proof that our specific products will produce the same results. We encourage you to discuss any cognitive health concerns with your healthcare provider. See our full Disclaimer for more information.